Sensitive and Insensitive Causation

Training Context - Insensitive versus Context - Sensitive

Tetrodotoxin-sensitive and -insensitive action potentials in myotubes.

The study of long-term cultures of myogenic cells has proven that electrical excitability develops only after the development of electrical coupling between the cells. That is, neither surface contact in itself nor coupling in itself is sufficient to cause excitability to develop in these cells. Following the formation of multinucleated myotubes, several different types of electrical responses ...

Immunological distinction between calmodulin-sensitive and calmodulin-insensitive adenylate cyclases.

Previous studies using calmodulin-Sepharose affinity chromatography have suggested that bovine brain may contain a mixture of calmodulin-sensitive and -insensitive adenylate cyclase activities (Wescott, K. R., La Porte, D. C., and Storm, D. R. (1979) Proc. Natl. Acad. Sci. U.S.A. 82, 3086-3090). In this study, mice were immunized with a purified preparation of the calmodulin-sensitive adenylate...

Strychnine-sensitive and -insensitive inhibitions in the cat's retina.

Effects of strychnine on intraretinal inhibition were investigated by recording unitary discharges from the optic tract fibers. Units were classed as on, off and on off according to their discharge patterns in response to diffuse illumination of the retina. Strychnine enhanced the firing rate of spontaneous discharge in the dark. ' On' inhibition of an off unit was greatly suppressed by strychn...

Distinct mechanosensitive properties of capsaicin-sensitive and -insensitive sensory neurons.

Mechanical stimulation of the somata of cultured neonatal rat dorsal root ganglia (DRG) neurons evoked inward cationic currents that displayed distinct properties between different subsets of cells. The presumptive nociceptor population, defined by capsaicin sensitivity, showed higher thresholds for the induction of an inward current and lower peak currents than other mechanosensitive neurons. ...